Radioimmunoassay of the group-specific antigen in detection of avian leukosis virus infection.

نویسندگان

  • K Sandelin
  • T Estola
  • S Ristimäki
  • E Ruoslahti
  • A Vaheri
چکیده

The major group-specific antigen (gs-a) of avian leukoviruses was detected by radioimmunoassay in extracellular medium of all embryonic cultures prepared from infected chickens. Embryos of birds not carrying an avian ]eukosis virus infection and of chickens from a leukosis-free flock could thus clearly be distinguished from infected ones. Release of group-specific antigen into the extracellular medium was independent of subgroup or strain of avian leukosis or Rous sarcoma virus. The radioimmunoassay of the group-specific antigen seems to be well suited to complement the COFAL (complement fixation avian leukosis) and RIF (resistance inducing factor) tests in the detection of leukosis virus in infected material.

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عنوان ژورنال:
  • The Journal of general virology

دوره 25 3  شماره 

صفحات  -

تاریخ انتشار 1974